胡霽    助理教授、研究員
所在學院生命科學與技術學院
研究方向行為的神經環路機制
聯系方式huji@@shanghaitech.edu.cn


 
 個人簡介 
2003年本科畢業于華中科技大學,同年進入中科院上海神經科學研究所。2005年隨導師實驗室轉至北京生命科學研究所(NIBS)/中科院生物物理研究所,2008年獲神經生物學博士學位。2009年開始在麻省理工學院Picower學習與記憶研究所(The Picower Institute for Learning and Memory at MIT )進行博士后研究工作。2013年1月回國,任職西安交通大學前沿科學技術研究院。2014年4月加入上??萍即髮W生命科學與技術學院任助理教授、研究員。
 主要研究內容 
我們發展和應用光學成像、神經調控、遺傳學標記與神經環路示蹤等最新的方法精確地研究情感及其相關的精神類疾病的重要科學問題。實驗室擁有國際領先且全面的光學成像儀器(雙光子顯微鏡、梯度折射透鏡、光纖光度測量)和技術手段,同時也將結合單細胞測序,質譜技術等前沿的分子生物學手段,深入研究以下重要的神經科學問題:1.應激/壓力的神經機制;2.神經精神藥理的環路機制;3. 神經與精神疾病治療的新策略。我們的研究將有助于重要的精神疾病比如抑郁癥、焦慮癥的治療。
 代表性論文 

Research Articles *系通訊作者)

1. Shouhua Zhang; Fei Lv; Yuan Yuan; Chengyu Fan; Jiang Li; Wenzhi Sun; Ji Hu*, Whole-brain Mapping of Monosynaptic Afferent Inputs to Cortical CRH Neurons, Frontiers in Neuroscience (2019)

2. Zheng-dong Zhao; Zongming Chen; Xinkuan Xiang; Mengna Hu; Hengchang Xie; Xiaoning Jia; Fang Cai; Yuting Cui; Zijun Chen; Lechen Qian; Jiashu Liu; Congping Shang; Yiqing Yang; Xinyan Ni; Wenzhi Sun; Ji Hu; Peng Cao; Haohong Li; Wei L Shen, Zona incerta GABAergic neurons integrate prey-related sensory signals and induce an appetitive drive to promote hunting, Nature Neuroscience (2019)

3. Haibin Zhou; Shouhua Zhang; Fei Lv; Wenzhi Sun; Lihua Wang; Chunhai Fan; Jiang Li*; Ji Hu*, Citrateassisted efficient local delivery of naked oligonucleotide into live mouse brain cells, Cell Proliferation, 2019, e12622

4. Xin-Yu Su; Ming Chen; Yuan Yuan; Ying Li; Su-Shan Guo; Huo-Qing Luo; Huang Cheng; Wenzhi Sun; Yong Li; Michael X. Zhu; Ming-Gang Liu*Ji Hu*; Tian-Le Xu*, Central Processing of Itch in the Midbrain Reward Center, Neuron (2019)

5. Yuan Yuan; Wei Wu; Ming Chen; Fang Cai; Chengyu Fan; Wei Shen; Wenzhi Sun*Ji Hu*, Reward Inhibits Paraventricular CRH Neurons to Relieve Stress, Current Biology, 2019, 29: 1~9

6. Rongfeng Hu; Juen Zhang; Minmin Luo; Ji Hu*, Response Patterns of GABAergic Neurons in the Anterior Piriform Cortex of Awake Mice, Cerebral Cortex, 2017.6.1, 27(6): 3110~3124

7. Rongfeng Hu; Sen Jin; Xiaobin He; Fuqiang Xu; Ji Hu*, Whole-Brain Monosynaptic Afferent Inputs to Basal Forebrain Cholinergic System, Frontiers in Neuroanatomy, 2016.10.10, 10: 0~98

8. Andrii Rudenko; Jinsoo Seo; Ji Hu; Susan C Su; Froylan Calderon de Anda; Omer Durak; Maria Ericsson; Marie Carlén; Li-Huei Tsai, Loss of cyclin-dependent kinase 5 from parvalbumin interneurons leads to hyperinhibition, decreased anxiety, and memory impairment, Journal of Neuroscience (2015)

9. Tao Chen, Kohei Koga, Giannina Descalzi, Shuang Qiu, Jian Wang, Le-Shi Zhang, Zhi-Jian Zhang, Xiao-Bin He, Xin Qin, Fu-Qiang Xu, Ji Hu, Feng Wei, Richard L Huganir, Yun-Qing Li; Min Zhuo,Postsynaptic potentiation of corticospinal projecting neurons in the anterior cingulate cortex after nerve injury, Molecular Pain, 2014, 10:33

10. Rong Gong#; Cheng Ding#; Ji Hu#; Yao Lu; Fei Liu; Elizabeth Mann; Fuqiang Xu,; Mitchell B. Cohen; Minmin Luo, Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior, Science, 2011.9.16, 333(6049): 1642~1646 (#co-first author)

11. Lili Gao; Ji Hu; Chun Zhong; Minmin Luo, Integration of CO2 and odorant signals in the mouse olfactory bulb, Neuroscience, 2011, 3(27):881-892

12. Ji Hu#; Chun Zhong#; Cheng Ding; Qiuyi Chi; Andreas Walz; Peter Mombaerts; Hiroaki Matsunami; Minmin Luo(*), Detection of near-atmospheric concentrations of CO2 by an olfactory subsystem in the mouse, Science, 2007.8.17, 317(5840): 953~957(#co-first author)

13. Liming Sun; Huayi Wang; Ji Hu; Jinlong Han; Hiroaki Matsunami; Minmin Luo, Guanylyl cyclase-D in the olfactory CO2 neurons is activated by bicarbonate, Proceedings of the National Academy of Sciences of the United States of America, 2009.2.10, 106(6): 2041~2046

  

Review article*系通訊作者)

14. Fang Luo; Yin Wei; Ziyue Wang; Minmin Luo; Ji Hu*, Genetically encoded neural activity indicators, Brain Science Advances, (2018)

15. Yan Yang; Hao Wang; Ji Hu*; Hailan Hu*, Lateral habenula in the pathophysiology of depression, Current Opinion in Neurobiology, 2018.02, 48: 90~96, (*co-corresponding author)

16. Minmin Luo; Liming Sun; Ji HuNeural detection of gases--carbon dioxide, oxygen--in vertebrates and invertebratesCurrent Opinion in Neurobiology, 2009.8, 19(4): 354~361 

                                 

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